RIFM Publishes Endpoint-Specific Read-Across Paper on Fragrance Ingredient Testing

Jan 10th, 2023

Holger Moustakas, Ph.D., shared, “[Endpoint specificity in read-across analog selection] expands the potential read-across options RIFM scientists have, which allows them to ensure the safety of more fragrance ingredients while avoiding extra testing and saving animal lives.”

DREAMSTIME

In 2022, the Research Institute for Fragrance Materials (RIFM) had a record-breaking year in terms of research papers being published in peer-reviewed journals.

One of the 12 published papers was penned by RIFM’s Computational Chemistry lead scientist Holger Moustakas, Ph.D., alongside a team of RIFM scientists and Expert Panel for Fragrance Safety members, published “An Endpoint-Specific Framework for Read-Across Analog Selection for Human Health Effects” in the peer-reviewed journal Chemical Research in Toxicology.

Read-across is a safety assessment approach in which study data on one chemical can be used as a proxy to support the safe use of a structurally similar chemical lacking study data.

Moustakas discussed the importance and impact of the research, “Endpoint specificity in read-across analog selection makes read-across a more scientific process. In addition, it expands the potential read-across options RIFM scientists have, which allows them to ensure the safety of more fragrance ingredients while avoiding extra testing and saving animal lives.”