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Section: Fragrance > Regulatory & Research

Monell Identifies the Scent of Skin Cancer

The Monell Chemical Senses Center may have identified the odor of skin cancer, a discovery that might be used to develop new ways of identifying basal cell carcinoma.

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Monell Center Appoints New Director

Nancy E. Rawson, PhD is Monell Center's new associate director, effective immediately.

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Patent Pick: Acetophenone-based F&F Materials

Patent Picks are chosen by the editors from publicly available sources. Today's feature, from Symrise and co-inventors, describes compositions using acetophenone derivatives to dissolve flavors, fragrances and lipophilic compounds.

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Patent Pick: Pro-fragrance Ketones

Patent Picks are chosen by the editors from publicly available sources. Today's highlight from Henkel includes specific ketones that act as photolabile pro-fragrances.

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Patent Pick: Ketone Room Freshening

Patent Picks are chosen by the editors from publicly available sources. Today's feature relates to ketones and their use for extending the scent of room fresheners.

Total syntheses of spirovetivanes and khusimone

The majority of these substances belong to the sesquiterpene group of natural products. Among these α-vetivone, β-vetivone, the norsesquiterpene khusimone, and three biogenetically derived C12-ketones provided the most exciting chemistry. Since the spiroketone and khusimone appear to play a significant role in the reconstitution of the essential oil, we have developed total syntheses of these substances. In an earlier synthesis of the spiroketone, β-vetivone was utilized as starting material; and more recently it has also been prepared by a photochemical route. Among the many published syntheses of β-vetivone two deserve special mention because of their elegance and stereo selectivity.

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Monell, Jefferson Forge Research Partnership

The organizations aim to expand the scope of Monell’s research and more readily translate its discoveries into policy.

RIFM president James Romine, Ph.D.; Sheila Romine; Laure Moutet Manheimer; with Kerry executives Steven Manheimer; Otis Curtis V; Rajesh Potineni, Ph.D.; and Michael Kemp, Ph.D., at the Double Tasty dinner. Kerry was a major supporter of the 50th Anniversary celebration and ITTSD conference.

Monell Center Celebrates 50 Years With Sensory Conference

The conference featured discussions on creating a guide to treating smell and taste disorders and how to improve the care and management of these conditions.

These fragrances are marketed for their mood-enhancing and wellness properties.

Functional Fragrances Gain Traction in Indonesia: Data

These fragrances are gaining traction amid growing awareness about mental health and increased stress levels.

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Ned Sharpless to Serve as Acting FDA Commissioner

The announcement comes following the resignation of Scott Gottlieb, who devoted his tenure to addressing youth e-cigarette use and modernizing food safety.

Effects of Structural Modifications on the Odour of Jasmone Analogues

The odour of 2-alkylcyclopentanones can be radically affected by substituents on the first or second carbon atoms of the side chain, substituents further along the chain having a much lesser effect on the odour character. It is postulated that these effects could be rationalised in terms of obstruction of the carbonyl group by a substituent on the first carbon of the side chain or disruption of the side chain conformation by one on the second position

Monell Center Researchers, Collaborators ID Critical Olfactory Protein

Researchers found that mice can't smell without G γ13, which may provide insight into the underlying causes of certain smell disorders in humans.

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[gallery] Givaudan Opens Indonesian Commercial and Development Center

Measuring at 2,600 square meters, the commercial and development center will allow the company to serve customers across a wide range of food, beverage and consumer good segments. This will allow Givaudan to offer its full range of flavor and fragrance creations and application development capabilities to the Indonesia market.

Monell-Led Research Identifies Scent of Melanoma

A nano-sensor was able to distinguish differences in volatile organic compounds, many of which are odorous, from normal and several different types of melanoma cells.

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Smelling With Your Tongue? Monell Center Investigates

A study from the Monell Chemical Senses Center has found that human taste cells contain many key molecules that are present in olfactory receptors.

Pheromone-Touting Fragrances Don't Work ... Yet

Study debunks myths, points way to a quantifiable effect on mood.

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[Podcast] A Whiff of Scent Science With Nancy Rawson of Monell

In this episode of Two Sense, we speak with Monell's Associate Director Nancy Rawson, Ph.D., an olfactory cell biologist, to learn more about the latest research in anosmia and why smell is critical to our livelihoods.

Unsaturated Components in the Essential Oil of Anthemis nobilis L. (Roman Chamomile)

French authors recently presented their analytical findings on the oil using the negative chemical ionization technique in mass spectrometry. They tracked the GLC profile of the complete oil with the mass numbers of the quasi-molecular ions [M-H]- in combination with the carboxylate anion RCOO-. Thereby inter alia the presence of five esters derived from methacrylic or crotonic acid was reported, however, without giving definite structural assignments for the individual components. The same holds for eight esters of the angelate or tiglate type, respectively. We have worked in a more traditional way and wish here to present the results concerning some of these methacrylates, crotonates, angelates and tiglates. All esters mentioned by us have proved by comparison with authentic synthetically prepared samples.

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