The Longevity Race to Slow Aging

Instead of aiming to reverse aging—although regenerative solutions are making strides in that area—slow aging prioritizes building resilience and delaying age-related issues.
Instead of aiming to reverse aging—although regenerative solutions are making strides in that area—slow aging prioritizes building resilience and delaying age-related issues.
annanahabed at Adobe Stock

The slow aging movement has picked up momentum since the pandemic, focusing on decelerating and mitigating the effects of natural biological processes and environmental exposures over a lifetime. Instead of aiming to reverse aging—although regenerative solutions are making strides in that area—slow aging prioritizes building resilience and delaying age-related issues. This approach emphasizes optimizing biological functions and minimizing exposure to elements that accelerate aging, benefiting the skin, hair and overall body health.

“The anti-aging narrative is now being replaced by well-aging and longevity beauty, a shift that emphasizes skin strength, radiance and biological respect,” says Irena James, senior business development manager, beauty and personal care, ingredients and specialties, Univar Solutions. “Rather than overcorrecting, today’s consumers value maintaining skin in its best form over time.”

This report delves into key innovation opportunities that brands can leverage to provide impactful solutions for consumers while distinguishing themselves from the competition.

Tatcha and Nivea Take on Skin Aging with Science-Powered Formulations

In August 2025, Tatcha made a significant pivot into the slow-aging era with the release of The Longevity Serum Skin Strength & Resilience Treatment, designed to boost cellular resilience, reduce aging senescent cell markers by 55%, firm and smooth the skin within 1 week for a “collagen-rich appearance,” and boost skin barrier strength instantly.

The formulation comprises the brand’s Okinawa Cellescence Complex, comprising noni juice for cellular renewal, soothing inflammation and reinforcing the skin barrier, as well as shell ginger for collagen defense and enhanced elasticity, and antioxidant-rich shikuwasa lime for brightening and skin-shielding benefits.

Beiersdorf has entered the skin longevity market with the launch of its Nivea Cellular Epigenetics Rejuvenating Serum.Beiersdorf has entered the skin longevity market with the launch of its Nivea Cellular Epigenetics Rejuvenating Serum. BeiersdorfBeiersdorf has entered the skin longevity market with the launch of its Nivea Cellular Epigenetics Rejuvenating Serum. Per the brand, the Nivea serum slows down the skin aging process at the cellular level, allowing for a reversal of skin age in two weeks.

The serum features Epicelline, the company’s proprietary epigenetic ingredient, which is said to reverse skin aging and promote skin longevity. According to Beiersdorf, Epicelline works by neutralizing and reversing the effects of external aging factors, rejuvenating skin cells in the process. The formulation also comprises three types of hyaluronic acid.

“Our patented skin-specific age clock technology helps us to identify active ingredients and solutions that make people look younger than they really are,” said Gitta Neufang, Ph.D., chief research and development officer at Beiersdorf. “By leveraging our scientific expertise in the field of epigenetics, our aim is to enhance and restore the youthful functions of aged skin cells.”

These are just two recent examples of the growing race to meet the rising demand for skin longevity and anti-aging solutions. To drive the next wave of innovation in this space, numerous suppliers have introduced cutting-edge solutions designed to support product development.

The Slow-aging x Longevity Toolbox

Zombie Cells, Collagen Boosts and Ageless Skin

Univar’s James notes that DSM-Firmenich’s Eterwell Youth is designed to reduce the appearance of tired, uneven or dull skin by targeting zombie cells, thereby reversing the age appearance of the skin by nine years within three months, per the supplier. It also supports skin quality and tone over time.

DSM-Firmenich has also developed Syn-Coll CB, a tripeptide that supports the skin’s structural appearance by helping to reinforce its natural matrix. At just 1%, the ingredient has reportedly been clinically shown to boost and safeguard collagen reserves while reducing UV-induced collagen degradation, slowing the skin aging process by mimicking the body's own mechanisms.  

Syn-Coll CB adapts to address collagen-related needs across different age groups, per DSM-Firmenich, and improves skin firmness and smoothness, sculpting skin for a youthful, rejuvenated appearance.  

Age-Defying Magic from Pomegranates

Drawing from the resilience of the pomegranate tree (Punica granatum), a symbol of vitality for centuries, Aethelis Granata optimizes the skin’s self-repair mechanisms.Drawing from the resilience of the pomegranate tree (Punica granatum), a symbol of vitality for centuries, Aethelis Granata optimizes the skin’s self-repair mechanisms. fotoduets at Adobe StockNaolys has unveiled Aethelis Granata, an innovative ingredient that leverages the power of pomegranate-derived exosomes to address skin aging at its core. By activating the skin's cellular communication pathways and promoting epigenetic regulation, this cutting-edge ingredient promises to transform anti-aging skin care formulations.

Drawing from the resilience of the pomegranate tree (Punica granatum), a symbol of vitality for centuries, Aethelis Granata optimizes the skin’s self-repair mechanisms. According to the company, key effects include the following:

  • SUMOylation activation: At the heart of Aethelis Granata’s efficacy lies the modulation of SUMOylation, a key epigenetic process that repairs DNA, enhances mitochondrial function and reorganizes chromatin structures in keratinocytes.
  • Holistic effects: By stimulating keratinocyte pathways and activating dermal fibroblasts, the ingredient enhances macromolecule synthesis, improving intercellular communication and regenerating skin structure.
  • Visible results: Clinical and in vitro studies demonstrate reduced wrinkles, improved hydration and smoother texture, delivering visibly rejuvenated skin.

Aethelis Granata offers comprehensive benefits for advanced skin care formulations, including:

  • anti-wrinkle
  • regenerating
  • restructuring
  • boosting cellular energy
  • hydrating to maintain resilience
  • energizing and revitalizing skin
  • calming skin under stress

This ingredient is therefore suggested for products targeting skin longevity and rejuvenation by optimizing cellular regeneration and maintaining skin homeostasis.

Effective at levels starting from 0.5%, the ingredient has been shown through extensive clinical and in vitro evaluations to support the following claims.

  • Hydration: Long-lasting enhancement; replenishes moisture barriers.
  • Wrinkle reduction: Rejuvenated skin appearance with visible wrinkle transformation.
  • Dermal energy boost: Mitochondrial function improvements empower skin vitality.

Vegan Biomimetic Exosomes for Skin Renewal

'Consumers desire effective, ethical skin care,' says Alexandre Lapeyre, Algaktiv’s marketing director. 'Exometics G represents a leap forward in delivering scientifically validated exosomes for next-generation skin care.'"Consumers desire effective, ethical skin care," says Alexandre Lapeyre, Algaktiv’s marketing director. "Exometics G represents a leap forward in delivering scientifically validated exosomes for next-generation skin care."zinkevych at Adobe StockAlgaktiv has introduced Exometics G, a "revolutionary" biomimetic exosome technology derived from microalgae. According to the company, this innovation delivers exceptional benefits for skin renewal, elasticity and anti-aging while addressing ethical and regulatory concerns of traditional exosomes.

Per Algaktiv, unlike existing solutions with inconsistent concentrations, Exometics G is precisely dosed at more than 10 billion vesicles per milliliter, allowing brands to claim more than 10 million exosomes per drop in their products. With a controlled particle size of 150 nm for optimal delivery, Exometics G is said to set a new standard for skin care.

Additional advantages are as follows:

  • Vegan and cruelty-free: No animal or human-derived materials.
  • High concentration: More than 10 million vesicles per drop for proven efficacy.
  • Sustainable and scalable: Lab-grown with limitless production capacity.
  • Patented technology: Ensures consistency and maximum potency.

According to Jordi Ayats, product director at Algaktiv, "Exometics G overcomes the limitations of traditional exosomes, providing a standardized, high-potency alternative."

Exometics G demonstrates significant improvements in skin renewal and rejuvenation, the company reports, including:

  • 30.6% faster wound healing in eight hours
  • visible firming effects, as measured by Cutometer
  • a 2.2-year reversal of wrinkles in 14 days
  • a 300% improvement in skin smoothness vs. placebo after 56 days
  • a 25% reduction in hyperpigmentation after 56 days
  • a 15% increase in skin radiance in 28 days

"Consumers desire effective, ethical skin care," says Alexandre Lapeyre, Algaktiv’s marketing director. "Exometics G represents a leap forward in delivering scientifically validated exosomes for next-generation skin care."

Bakuchiol Boost: New Natural Heroes for Radiant, Clear Skin

Sharon Personal Care by Eternis has introduced two new bakuchiol-based ingredients designed to enhance natural skin care: Pantrofina Baokiol RSPO MB and Pantrofina BakuClear RSPO MB. Both ingredients offer the benefits of bakuchiol, a natural alternative to retinol, targeting aging and blemish-prone skin.  

Pantrofina Baokiol RSPO MB is a 100% natural, oil-based and non-irritating alternative to retinol. It targets signs of aging and is suitable for use in skin care, makeup, and body care products. Clinical studies reveal that it:  

  • reduces wrinkles 50% more effectively than retinol,  
  • smooths skin
  • boosts radiance
  • is gentle enough for daily use

It is also COSMOS and Natrue certified.  

Pantrofina BakuClear RSPO MB, meanwhile, is a water-based bakuchiol solution designed for oily and acne-prone skin. It offers sebum-balancing effects, reducing acne spot volume by 13% and sebum levels by up to 15%. It is effective, non-irritating and supports clear, water-based formulations. Like Baokiol, it is 100% natural and COSMOS/Natrue certified.  

Taurine-Powered Skin Care

BASF's Oximony, based on FairWild certified Lysimachia christinae flower/leaf/stem extract), is designed to boost skin longevity by promoting healthy levels of taurine and taurine transporter TAUT, as well as NAD+. Taurine is a naturally occurring amino acid that can boost hydration and antioxidant protection while reducing inflammation.

The ingredient is also said to reduce senescence markers (p16, β-galactosidase), the senescence-associated secretory phenotype SASP (MMP1, MMP3, IL-6, IL-8), and the CXCR2 receptor.

In these ways, Oximony is designed to help restore skin radiance, resilience and firmness. A 0.25% concentration of the ingredient applied in Chinese volunteers showed a 28% improvement in fatigued appearance within two weeks of application. Skin firmness also increased by 17% after one month, while radiance improved by 18% over the baseline after two months.

A Flower-Powered Secret Weapon for Radiant, Firm Skin

Silab recently disclosed new efficacy data for its Oxygeskin active ingredient derived from the nasturtium flower.Silab recently disclosed new efficacy data for its Oxygeskin active ingredient derived from the nasturtium flower.Olena Svechkova at Adobe StockSilab recently disclosed new efficacy data for its Oxygeskin active ingredient derived from the nasturtium flower. When tested at 0.25% on aged human fibroblasts, the ingredient was found to "significantly reduce the expression of miRNAs" repressing key biological pathways, including oxygenation (HIF-1α) and cellular energy production (ATP), as well as those essential to dermal and epidermal homeostasis.

These findings come in addition to the ingredient's previously described ability to revive complexion radiance by reinvigorating skin oxygenation in conditions of chronological aging or digital pollution.

Silab also investigated the effect of Oxygeskin in body skin. After 14 days of twice daily application of a formulation incorporating 1% of the ingredient to the thighs, skin oxygenation was boosted by 4.5%.

The skin's microrelief was also diminished by 6.3% in the treated areas; 89% of trial participants considered their skin to feel velvety; 83% reported their skin was more radiant; and 89% found it appeared more beautiful. Finally, skin firmness was improved by 7%.

Skin Longevity Unlocked: Natural Actives for Ageless Radiance

Solabia’s latest active ingredients address the increasing demand for solutions catering to the biological and emotional aspects of aging.

Pro-Longevia (INCI: Glycerin (and) Water (Aqua) (and) Rubus Idaeus Leaf Extract) is a raspberry leaf-derived active targeting the hallmarks of aging. The 100% natural ingredient is said to preserve mitochondrial function, balance oxidative defenses and enhance protein homeostasis. This, in turn, reportedly visibly reduce skin roughness, pigmentation irregularities and wrinkles.

Peptiskin (INCI: Arginine/Lysine Polypeptide) is a naturally derived oligopeptide designed to protect dermal and epidermal structures, stimulate extracellular matrix components, and combat cellular senescence. Clinically tested, it has been shown to visibly improve skin texture, firmness and radiance within a month, per the company.

FucoLife GR (INCI: Maltodextrin (and) Biosaccharide Gum-3) is a polysaccharide derived through eco-friendly bacterial fermentation. It reportedly addresses both physical and emotional well-being for menopausal skin. Per the company, it is proven to restore skin integrity, reduce wrinkles and enhance self-esteem by targeting neurocosmetic pathways.

Next-Gen Hyaluronic Acids: Fighting Wrinkles, Boosting Skin and Saving the Planet

According to Givaudan, PrimalHyal UltraReverse has been shown to increase sirtuin 1 by 136% and collagen 1 by 48%, which can contribute to reduced signs of aging.According to Givaudan, PrimalHyal UltraReverse has been shown to increase sirtuin 1 by 136% and collagen 1 by 48%, which can contribute to reduced signs of aging.Bidzilya at Adobe StockGivaudan Active Beauty recently launched PrimalHyal UltraReverse. According to the company, the product is the smallest and most sustainable hyaluronic acid developed to date, capable of penetrating skin cells at the DNA level to tackle the primary hallmarks of aging.

PrimalHyal UltraReverse specifically targets four critical pathways to combat chronological aging and protect skin from environmental stressors, known collectively as the exposome.

More specifically, it addresses:

  • Epigenetic control: Restoring DNA methylation processes while enhancing sirtuin expression and activity, reducing cryptic transcription.
  • Genomic instability: Strengthening DNA repair mechanisms to promote healthier, more resilient skin.
  • Telomere attrition: Reactivating telomerase expression and activity, preserving chromosome integrity and cellular longevity.
  • Loss of proteostasis: Enhancing proteasome activity to maintain optimal cellular function and balance.

According to Givaudan, PrimalHyal UltraReverse has been shown to increase sirtuin 1 by 136% and collagen 1 by 48%, which can contribute to reduced signs of aging. The ingredient was designed for its ultra-low molecular weight, achieved through advanced precision fermentation, which also reduces its environmental impact.

Elsewhere, Se(HA)+ from LipoTrue is a naturally enriched HA ferment derived from a bacteria that inherently encodes the HAS enzyme that synthesizes hyaluronic acid. This process allows the ingredient manufacturer to obtain an enriched HA ferment with a broad spectrum composition that provide both HA-like and HA-booster efficacies. Se(HA)+ offers a sustainable and natural alternative.

Se(HA)+ enhances barrier function and epidermal regeneration in the upper layers of the skin, while also boosting endogenous HA synthesis, preventing dehydration and renewing the extracellular matrix (collagen, elastin, fibrillin) in deeper layers. In vivo studies have shown improvements in moisturization, reduction of crow’s feet and nasolabial wrinkles, and a plumping effect on the lips.

Supercharged Ingredients for Sustainable Skin Care

Chemyunion's portfolio of cosmetic ingredients developed using supercritical CO₂ extraction offers enhanced sustainability and skin-friendly benefits.

Revinage MB (INCI: Bidens Pilosa Extract (and) Elaeis Guineensis (Palm) Oil (and) Gossypium Herbaceum (Cotton) Seed Oil (and) Linum Usitatissimum (Linseed) Seed Oil) is a plant-derived alternative to retinoids obtained from Bidens pilosa. It reportedly helps to improve the appearance of wrinkles, support a more even skin tone and improve lip texture. According to the company, unlike synthetic retinoids, it is suitable for use on all skin types, including sensitive skin, and does not carry the same potential for irritation.

Physavie 250 MB (INCI: Physalis Angulata Extract (and) Caprylic/Capric Triglyceride) is recommended for sensitive or reactive skin. It has soothing and anti-inflammatory properties comparable to corticosteroids. COSMOS approved, the ingredient has been shown to support the extracellular matrix while offering protection against environmental stressors such as blue light and infrared radiation, per the company. It can also be incorporated into sun care products to enhance protection without affecting SPF performance.

Finally, Agen (INCI: Canola Oil (and) Malus Domestica Fruit Extract (and) Zingiber Officinale (Ginger) Extract) is described as a synergistic combination of apple extract and supercritical extract of ginger. It acts epigenetically to improve skin firmness and elasticity, and to redensify the skin.

A Nature-Derived Solution for Dry, Sensitive and Retinol-Treated Skin

Silab's Neolipyl was developed to help restore the lipid matrix of dry skin and, when used in combination with retinol, mitigate irritation.Silab's Neolipyl was developed to help restore the lipid matrix of dry skin and, when used in combination with retinol, mitigate irritation.zigres at Adobe StockSilab has introduced Neolipyl, a natural active derived through an enzymatic extraction process from the flowering tops of Centaurea cyanus (cornflower) sourced from certified organic French agriculture. The ingredient was developed to help restore the lipid matrix of dry skin and, when used in combination with retinol, mitigate irritation.

Using lipidomic analysis and optical biopsy modeling, Silab established a profile of dry skin characterized by impaired lipid synthesis and disordered lipid structure. Neolipyl (INCI: Water (Aqua) (and) Glycerin (and) Centaurea Cyanus Flower Extract) was developed and tested using this model. Results indicated the active: stimulated epidermal lipid production and improved lipid organization, contributing to the restoration of barrier integrity.

In addition, in clinical studies of Caucasian and Asian subjects with dry skin, Neolipyl was reportedly shown to improve hydration, comfort and skin surface smoothness after 14 days of twice daily use. Its performance was comparable to niacinamide in restoring barrier function.

When applied alongside retinol on normal skin, Neolipyl helped to reduce adverse effects such as dryness, redness and discomfort, while maintaining retinol’s anti-aging efficacy, the company reports. It also visibly enhanced skin radiance.

Neolipyl is available in aqueous solution and recommended at concentrations between 0.5% and 2%. Additional benefits of the ingredient include: 100% natural origin content designation per ISO 16128; complies with biodiversity requirements; and meets global cosmetic regulations, including those in the EU, U.S., China and Japan.

Thus, by supporting lipid balance and skin tolerance, Neolipyl offers a nature-derived option for formulations targeting dry, sensitive or retinol-treated skin.

Peony Power for Even Skin Tone

Ichimaru Pharcos recently launched PeoGlow, a natural active ingredient derived from peony root designed to address skin tone unevenness linked to the glycation process.Ichimaru Pharcos recently launched PeoGlow, a natural active ingredient derived from peony root designed to address skin tone unevenness linked to the glycation process.Pixel-Shot at Adobe StockIchimaru Pharcos recently launched PeoGlow, a natural active ingredient derived from peony root designed to address skin tone unevenness linked to the glycation process—specifically the interaction between Advanced Glycation End Products (AGEs) and their receptors (RAGE).

According to the company, PeoGlow (INCI: Butylene Glycol (and) Water (Aqua) (and) Paeonia Albiflora Root Extract) represents a breakthrough in skin tone care by targeting the glycation domino run — a chain reaction where AGEs bind to RAGE, triggering hyperpigmentation (brown), darkening (black) and dullness (gray). This mechanism is now understood to be a root cause of uneven skin tone, affecting both melanocytes and keratinocytes, per the company.

Key product claims and benefits supported by the ingredient include: inhibits AGEs-RAGE interaction; reduces AGEs-related brown pigmentation; disrupts AGEs-RAGE signaling associated with black and gray tone; and improves overall skin tone uniformity

Applicable across facial and body care, PeoGlow is said to be ideal for skin brightening, anti-aging, under-eye treatments, hand creams and body creams.

Additional formulating considerations are it yellowish brown to brown liquid form with a characteristic odor; recommended dosage at 1%; and its JSQI approved, Chinese IECIC 2021 listed and halal certified statuses.

Key Takeaways for Marketers and Product Developers 

The slow-aging movement and longevity-focused innovations represent a paradigm shift in consumer preferences, offering significant opportunities for marketers and product developers in the beauty and personal care industry. Here's what you need to know:  

1. Emphasize Skin Resilience and Longevity

Consumers are moving away from "anti-aging" narratives and seeking solutions that enhance overall skin health and longevity. Position your products to promote strength, resilience, and natural aging with grace.  

2. Leverage Science-Powered Ingredients 

The rise of advanced technologies like epigenetics, biomimetic exosomes and next-generation hyaluronic acids highlights the demand for solutions rooted in cutting-edge science. Incorporating clinically proven ingredients into formulations will enhance consumer trust and product efficacy.  

3. Natural and Sustainable Solutions are Non-Negotiable 

Consumers are increasingly prioritizing natural, vegan and sustainable products. Highlight these qualities in your marketing to align with ethical and environmentally conscious values.  

4. Personalization and Targeted Benefits 

Innovations like collagen boosters, pomegranate-derived exosomes or bakuchiol alternatives allow brands to target specific skin concerns. Offering personalized solutions tailored to diverse age groups and skin types can set your brand apart in a crowded market.  

5. Storytelling Around Innovation 

Consumers are drawn to products with compelling innovation stories. Highlight the unique science, heritage or nature-inspired processes behind your ingredients to build stronger emotional connections with your audience.  

By staying ahead of these trends and focusing on the intersection of science, sustainability, and personalization, brands can effectively meet the evolving demands of the slow-aging and longevity care market while distinguishing themselves as leaders in innovation.

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