The Research Institute for Fragrance Materials (RIFM) Safety Assessment Program has published peer-reviewed safety assessments covering over 2,000 fragrance materials in the peer-reviewed literature.
At RIFM's 58th Annual meeting held in September 2024, president Anne Marie Api, Ph.D., Fellow ATS, highlighted the achievement, “RIFM has published thousands of peer-reviewed datasheets, group summaries, evaluations, and research papers addressing the safe use of scent-producing ingredients since the early 1970s. In the 21st century, we pivoted to research and next-generation risk assessments (NGRAs) focused on animal-free science, strategically using new approach methodologies (NAMs) to save well over half a million animals.”
Danielle Botelho, Ph.D., director of Scientific Operations at RIFM added, “This milestone is significant, given that the complete palette of discrete fragrance ingredients is approximately 2,200 materials in any given year. In addition to the discrete materials, the fragrance-producing palette includes approximately 900 Natural Complex Substance (NCS) ingredients distilled from natural sources. RIFM anticipates completing safety assessments for the first round of NCS by 2028.”
