IITR Confirms Science-Based Safety Assessment Process

The independent reproduction of safety assessment is a critical step toward an internationally accepted standard to support the safe use of fragrances.
The independent reproduction of safety assessment is a critical step toward an internationally accepted standard to support the safe use of fragrances.

The Government of India’s Institute of Toxicology Research (IITR), a wing of the Council of Scientific and Industrial Research (CSIR), recently confirmed the science-based safety assessment process pioneered by the Research Institute of Fragrance Materials (RIFM).

Related: RIFM’s Safety Science Featured at Toxicology Conference

The independent reproduction of safety assessment results from the same set of internationally accepted guidelines is a critical step toward an internationally accepted standard to support the safe use of fragrances, no matter where a consumer calls home.

RIFM’s work with IITR began at INCITE 2018, a fragrance safety stakeholder event held in Lucknow, India. At that event, RIFM’s President, James C. Romine, Ph.D., emphasized the value of international confirmation.

In the months that followed, CSIR-IITR scientists took on an evaluation exercise based on RIFM’s Safety Assessment Criteria paper, which reflects advances in risk assessment approaches and new and classical toxicological methodologies.

Using RIFM’s criteria, they analyzed and wrote up independent safety assessments for four ingredients to see how closely their conclusions would echo those of RIFM’s.

RIFM’s senior scientist of reproductive toxicology, Kaushal Joshi Ph.D., said, “CSIR-IITR’s analyses matched ours for the same ingredients. They recently published one of the analyses in their Annual Report for 2019-2020.”

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