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Type: Article

Section: Fragrance > Regulatory & Research

Epidermal Bioavailability of Volatile Compounds

Application to fragrance disposition and skin sensitization risk assessment.

As one of the most popular and expensive oils of the 19th century, violet oil’s compounds could be isolated into three major ionones. It was found that depending on the synthetic route, mixtures of the ionones in different ratios were formed, each of which had unique fragrance profiles.

Patenting Non-Naturally Occurring Fragrance Compounds

What does the patent literature tell us about innovation in the area of non-naturally occurring fragrance compounds? This short article provides some recent examples of U.S. patents that have claimed “new, useful and non-obvious” non-naturally occurring fragrance compounds or compositions.

Ozonolysis used for synthesis of odor compounds

This paper concerns, in particular, new or modified methods for the synthesis of odor compounds, drugs, and pesticides.

The biosynthesis of terpene compounds

From Wallach's isoprene rule to Ruzieka's biogenetic isoprene rule, the monoterpenes and sesquiterpenes have played a significant role in the development of basic concepts concerning the origin of all terpenoid compounds. Yet, while our understanding of the biosynthesis of higher terpenoids, such as steroids, has flourished progress in the biochemistry of monoterpenes and sesquiterpenes has been relatively slow--due in large part to the chemical nature of the mono- and sesquiterpenes (volatility, instability, and so forth) and to the experimental difficulties associated with the plants that produce these compounds.

3-Cyclohexylpropanal and 3-Cyclohexylbutanal as Raw Materials for Fragrant Compounds

This study reports an investigation of the hydrogenation of aromatic rings of these alcohols, leading to the respective 3-cyclohexyl-1-alkanols.

New compounds with small rings in essential oils

Despite the continuing discovery of new synthetic fragrance raw materials, essential oils still remain the other half of the foundation of perfumery. Consequently, the analysis of essential oils is still very much of interest, as is illustrated by the excellent series of articles by Lawrence in this journal. We now wish to report a number of products containing small (three-, four-, and five-membered) rings, most of which are found for the first time in essential oils. These products were isolated by chemical group separation, liquid and gas chromatography, whereupon the structures were determined by mass, infrared and NMR spectroscopy. All structures were confirmed by synthesis. The essential oils used were obtained from regular commercial sources.

Heterocyclic Compounds in Flavors and Fragrances Part Ill. Pyridine and Derivatives

During the last two decades the role of heterocyclic compounds in food flavors has been reviewed by several authors (18, 78, 79, 117-122). While furans (66), pyrroles (68), thiophenes (61), thiazoles (62, 63, 120), oxazoles (65, 57), Iactones (64), pyrazines (55, 56) and their reduced systems were periodically treated, surprisingly, pyridines which are among the most widely distributed volatile flavor compounds have not been described in detail (69). Therefore, the purpose of this review is to fill this gap.

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A Fresh Language

As the demand for basil continues to grow in a myriad of culinary, household and cosmetic products, developing an olfactory language will strengthen its position in the marketplace.

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A Natural and a Pod: Commonalities in Vanilla and Tea Processing

Shared chemistry, biochemistry and processing in tea leaf and vanilla pod.

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