Most Popular in:


Email This Item! Print This Item!

Special Feature: REACH and In Vitro Alternatives—Corrosive Potential Testing

Posted: November 28, 2007

page 5 of 7

2. C Grindon, R Combes, MT Cronin, DW Roberts and J Garrod, A review of the status of alternative approaches to animal testing and the development of integrated testing strategies for assessing the toxicity of chemicals under REACH: A summary of a DEFRA-funded project conducted by Liverpool John Moores University and FRAME, Alternatives to Laboratory Animals 34, Suppl. 1, 149-158 (2006)

3. OECD Guidelines for the Testing of Chemicals,No. 431: In Vitro Skin Corrosion: Human Skin Model Test. Paris, France: OECD, 8 p. (2004a)

4. M Liebsch, D Traue, C Barrabas, H Spielmann,P Uphill, S Wilkins, JP McPherson, C Wiemann, T Kaufmann, M Remmele, HG Holzhütter, The ECVAM prevalidation study on the use of EpiDerm for skin corrosivity testing. ATLA 28:371-401 (2000)

5. JH Draize, G Woodward and HO Clavery, Methods for the study of irritation and toxicity of substances applied topically to the skin and mucous membranes. J of Pharmacology and Experimental Therapeutics 82 377-390 (1944)

6. MK Robinson, JP McFadden and DA Basketter, Validity and ethics of the human 4-h patch test as an alternative to assess acute skin irritation potential, Contact Dermatitis 45(1) 1-12 (2001)