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Evolva Holding SA (Reinach, Switzerland) announced it has entered into an agreement with International Flavors & Fragrances Inc. (IFF) (New York) to implement a commercially viable biosynthetic route for the production of a key flavoring ingredient. Under the multi-year agreement, IFF will fund research and development activities at Evolva, focused primarily on the pathway and yield stages of the program through the scale-up and manufacturing phases. Evolva will receive an upfront technology access fee, as well as monthly research fees and milestone payments upon achieving certain goals in terms of yield and production volumes. IFF will commercialize the resulting product and Evolva will receive a royalty on product sales based on both margin and volume.