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1,1-Dimethoxy-2,2,5-trimethyl-4-hexene: The Grapefruit Acetal

By: Mchael Zviely, CIC
Posted: June 24, 2011, from the July 2011 issue of P&F magazine.

1,1-Dimethoxy-2,2,5-trimethyl-4-hexene (CAS# 67674-46-8) is a colorless to pale yellow liquid with a fresh, citrus, grapefruit peel-like odor and a vetiveryl acetate aspect. 1,1-Dimethoxy-2,2,5-trimethyl-4-hexene, which is not reported as being found in nature, belongs to a series of natural and synthetic molecules, of which nootkatone is a key material, that can represent the grapefruit note in fragrances. Both molecules show some structure similarity.

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