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Although other materials are known to display such a cooling effect, almost all of them are derivatives of l-menthol.
Organoleptically, l-menthol displays a light, minty, refreshing peppermint odor that at most practical concentrations is complicated by an intense olfactory numbing-cooling sensation. After exposure to menthol’s vapors for a while the nose becomes fatigued. The dual-sensory effect experienced makes both the odor and taste evaluation of menthol a difficult task. This decrease in one’s sharpness in smelling forces those who both QC batches of menthol production and also work in the area of flavor or fragrance creation to evaluate menthol samples at the end of their working day.